Role of glutamate receptors and glial cells in the pathophysiology of treatment-resistant depression

Keyphrases

• Pathophysiology 100%
• Glial Cells 100%
• Glutamate Receptors 100%
• Receptor Cells 100%
• Treatment-resistant Depression 100%
• Ketamine 71%
• Antidepressants 42%
• Astrocytes 42%
• Inflammatory Cytokines 28%
• Glutamate 28%
• Microglia 28%
• Monoaminergic 28%
• Glucocorticoid Receptor 28%
• Early Life Adversity 28%
• Response to Stress 14%
• Mechanism of Action 14%
• Adverse Events 14%
• Signaling Pathway 14%
• Inflammatory Process 14%
• Specific Mechanisms 14%
• Synaptic 14%
• Inflammatory Mediators 14%
• Microglial Activation 14%
• Brain Abnormalities 14%
• Neurotoxicity 14%
• Detrimental Effects 14%
• Treatment Effect 14%
• Adulthood 14%
• Brain-derived Neurotrophic Factor 14%
• Glutamatergic 14%
• Reuptake 14%
• N-methyl-D-aspartate Receptor Antagonist 14%
• Disease-specific 14%
• Synaptogenesis 14%
• Spill 14%
• Glutamatergic Receptors 14%
• Socioeconomic Burden 14%
• Glutamatergic Neurotransmission 14%
• Microglial Function 14%
• Glutamatergic Agents 14%
• Maladaptive Responses 14%
• Abusers 14%
• Glutamatergic Dysfunction 14%
• Extrasynaptic 14%
• Vulnerability to Stress 14%
• Extrasynaptic NMDA Receptors 14%

Neuroscience

• Glutamate Receptor 100%
• Microglia 100%
• Treatment-Resistant Depression 100%
• Ketamine 71%
• Astrocyte 42%
• Antidepressant 42%
• Proinflammatory Cytokine 28%
• Glutamic Acid 28%
• Glucocorticoid Receptor 28%
• Brain-Derived Neurotrophic Factor 14%
• Brain Abnormalities 14%
• Synaptic Transmission 14%
• NMDA Receptor 14%
• Reuptake 14%
• Excitotoxicity 14%
• NMDA Receptor Antagonist 14%
• Synaptogenesis 14%
• Receptor 14%