Rule generation using NN and GA for SARS-CoV cleavage site prediction

Yeon Jin Cho, Hyeoncheol Kim

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Cleavage site prediction is an important issue in molecular biology. We present a new method that generates prediction rules for SARS-CoV protease cleavage sites. Our method includes rule extraction from a trained neural network and then enhancing the extracted rules by genetic evolution to improve its quality. Experimental results show that the method could generate new rules for cleavage site prediction, which are more general and accurate than consensus patterns.

    Original languageEnglish
    Title of host publicationKnowledge-Based Intelligent Information and Engineering Systems - 9th International Conference, KES 2005, Proceedings
    PublisherSpringer Verlag
    Pages785-791
    Number of pages7
    ISBN (Print)3540288961, 9783540288961
    DOIs
    Publication statusPublished - 2005
    Event9th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2005 - Melbourne, Australia
    Duration: 2005 Sept 142005 Sept 16

    Publication series

    NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
    Volume3683 LNAI
    ISSN (Print)0302-9743
    ISSN (Electronic)1611-3349

    Other

    Other9th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2005
    Country/TerritoryAustralia
    CityMelbourne
    Period05/9/1405/9/16

    ASJC Scopus subject areas

    • Theoretical Computer Science
    • General Computer Science

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