Selective and sensitive TNT sensors using biomimetic polydiacetylene-coated CNT-FETs

Tae Hyun Kim; Byung Yang Lee; Justyn Jaworski; Keisuke Yokoyama; Woo Jae Chung; Eddie Wang; Seunghun Hong; Arun Majumdar; Seung Wuk Lee

doi:10.1021/nn103324p

Selective and sensitive TNT sensors using biomimetic polydiacetylene-coated CNT-FETs

Tae Hyun Kim, Byung Yang Lee, Justyn Jaworski, Keisuke Yokoyama, Woo Jae Chung, Eddie Wang, Seunghun Hong, Arun Majumdar, Seung Wuk Lee

Research output: Contribution to journal › Article › peer-review

142 Citations (Scopus)

Abstract

Miniaturized smart sensors that can perform sensitive and selective real-time monitoring of target analytes are tremendously valuable for various sensing applications. We developed selective nanocoatings by combining trinitrotoluene (TNT) receptors bound to conjugated polydiacetylene (PDA) polymers with single-walled carbon nanotube field-effect transistors (SWNT-FET). Selective binding events between the TNT molecules and phage display derived TNT receptors were effectively transduced to sensitive SWNT-FET conductance sensors through the PDA coating layers. The resulting sensors exhibited an unprecedented 1 fM sensitivity toward TNT in real time, with excellent selectivity over various similar aromatic compounds. Our biomimetic receptor coating approach may be useful for the development of sensitive and selective micro- and nanoelectronic sensor devices for various other target analytes.

Original language	English
Pages (from-to)	2824-2830
Number of pages	7
Journal	ACS nano
Volume	5
Issue number	4
DOIs	https://doi.org/10.1021/nn103324p
Publication status	Published - 2011 Apr 26
Externally published	Yes

Keywords

TNT sensor
carbon nanotube
lipid membrane receptor
polydiacetylene
trinitrotoluene

ASJC Scopus subject areas

Materials Science(all)
Engineering(all)
Physics and Astronomy(all)

Access to Document

10.1021/nn103324p

Cite this

@article{023e6b77a09048dc8c9bcb457bb3b132,

title = "Selective and sensitive TNT sensors using biomimetic polydiacetylene-coated CNT-FETs",

abstract = "Miniaturized smart sensors that can perform sensitive and selective real-time monitoring of target analytes are tremendously valuable for various sensing applications. We developed selective nanocoatings by combining trinitrotoluene (TNT) receptors bound to conjugated polydiacetylene (PDA) polymers with single-walled carbon nanotube field-effect transistors (SWNT-FET). Selective binding events between the TNT molecules and phage display derived TNT receptors were effectively transduced to sensitive SWNT-FET conductance sensors through the PDA coating layers. The resulting sensors exhibited an unprecedented 1 fM sensitivity toward TNT in real time, with excellent selectivity over various similar aromatic compounds. Our biomimetic receptor coating approach may be useful for the development of sensitive and selective micro- and nanoelectronic sensor devices for various other target analytes.",

keywords = "TNT sensor, carbon nanotube, lipid membrane receptor, polydiacetylene, trinitrotoluene",

author = "Kim, {Tae Hyun} and Lee, {Byung Yang} and Justyn Jaworski and Keisuke Yokoyama and Chung, {Woo Jae} and Eddie Wang and Seunghun Hong and Arun Majumdar and Lee, {Seung Wuk}",

year = "2011",

month = apr,

day = "26",

doi = "10.1021/nn103324p",

language = "English",

volume = "5",

pages = "2824--2830",

journal = "ACS nano",

issn = "1936-0851",

publisher = "American Chemical Society",

number = "4",

}

TY - JOUR

T1 - Selective and sensitive TNT sensors using biomimetic polydiacetylene-coated CNT-FETs

AU - Kim, Tae Hyun

AU - Lee, Byung Yang

AU - Jaworski, Justyn

AU - Yokoyama, Keisuke

AU - Chung, Woo Jae

AU - Wang, Eddie

AU - Hong, Seunghun

AU - Majumdar, Arun

AU - Lee, Seung Wuk

PY - 2011/4/26

Y1 - 2011/4/26

N2 - Miniaturized smart sensors that can perform sensitive and selective real-time monitoring of target analytes are tremendously valuable for various sensing applications. We developed selective nanocoatings by combining trinitrotoluene (TNT) receptors bound to conjugated polydiacetylene (PDA) polymers with single-walled carbon nanotube field-effect transistors (SWNT-FET). Selective binding events between the TNT molecules and phage display derived TNT receptors were effectively transduced to sensitive SWNT-FET conductance sensors through the PDA coating layers. The resulting sensors exhibited an unprecedented 1 fM sensitivity toward TNT in real time, with excellent selectivity over various similar aromatic compounds. Our biomimetic receptor coating approach may be useful for the development of sensitive and selective micro- and nanoelectronic sensor devices for various other target analytes.

AB - Miniaturized smart sensors that can perform sensitive and selective real-time monitoring of target analytes are tremendously valuable for various sensing applications. We developed selective nanocoatings by combining trinitrotoluene (TNT) receptors bound to conjugated polydiacetylene (PDA) polymers with single-walled carbon nanotube field-effect transistors (SWNT-FET). Selective binding events between the TNT molecules and phage display derived TNT receptors were effectively transduced to sensitive SWNT-FET conductance sensors through the PDA coating layers. The resulting sensors exhibited an unprecedented 1 fM sensitivity toward TNT in real time, with excellent selectivity over various similar aromatic compounds. Our biomimetic receptor coating approach may be useful for the development of sensitive and selective micro- and nanoelectronic sensor devices for various other target analytes.

KW - TNT sensor

KW - carbon nanotube

KW - lipid membrane receptor

KW - polydiacetylene

KW - trinitrotoluene

UR - http://www.scopus.com/inward/record.url?scp=79955380467&partnerID=8YFLogxK

U2 - 10.1021/nn103324p

DO - 10.1021/nn103324p

M3 - Article

C2 - 21361351

AN - SCOPUS:79955380467

SN - 1936-0851

VL - 5

SP - 2824

EP - 2830

JO - ACS nano

JF - ACS nano

IS - 4

ER -

Selective and sensitive TNT sensors using biomimetic polydiacetylene-coated CNT-FETs

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this