@inproceedings{08176a38b373467f96d18b4a1003b270,
title = "Sensitive, selective and resuable electrochemical sensor for mercury(II) based on molecular beacon approach",
abstract = "We have developed a sensitive and selective electrochemical sensor for the detection of mercury(II) ions in aqueous media. This electrochemical sensor is based on the molecular beacon which involves an electroactive, ferrocene-labeled DNA hairpin structure and provides strategically selective binding of thyminethymine mismatch for Hg2+ ions. The modified electrode showed a voltammetric signal due to an one-step redox reaction of the surface-confined ferrocenyl moiety. The {"}signal-on{"} upon mercury binding could be attributed to a change in conformation from open structure to restricted hairpin structure. The molecular beacon mercury(II) ion sensor was amenable to regeneration by unfolding the ferrocene-labeled DNA in 10 μM cysteine.",
keywords = "Electrochemical detection",
author = "Donghoon Han and Kim, {Yang Rae} and Oh, {Jeong Wook} and Kim, {Jong Seung} and Hasuck Kim",
year = "2009",
language = "English",
isbn = "9780979806421",
series = "Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Chemical and Biological Microsystems Society",
pages = "964--966",
booktitle = "Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
note = "13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 ; Conference date: 01-11-2009 Through 05-11-2009",
}