Serosurveillance of avian influenza A/H5N6 virus infection in poultry farmers, Gyeonggi Province, Republic of Korea, 2016–2017

Sukhyun Ryu, Chi Kyeong Kim, Kisoon Kim, Sang Hee Woo, Byung Chul Chun

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)


    Objectives: Between November 20, 2016 and April 17, 2017, outbreaks of highly pathogenic avian influenza (HPAI) A/H5N6 occurred on poultry farms in Gyeonggi Province in the Republic of Korea. A serosurvey was conducted among poultry farmers to identify the transmission of HPAI A/H5N6 virus to humans. Methods: A descriptive study of 870 poultry farmers in Gyeonggi Province in Korea was conducted during the 2016–2017 outbreaks. Serological testing was performed using a microneutralization (MN) assay for antibodies against influenza A/duck/ES2/Korea/2016 virus, which has antigenic properties similar to those of the HPAI A/H5N6 virus that caused this poultry outbreak. Results: Overall, 523 exposed poultry farmers were assessed by serological testing. Consequently, all tested negative for HPAI A/H5N6 virus via MN assay. Conclusions: Based on serological assays, no transmission of HPAI A/H5N6 to humans was identified in this study cohort. Additional studies should be conducted to determine the possibility of poultry-to-human transmission of HPAI A/H5N6.

    Original languageEnglish
    Pages (from-to)49-51
    Number of pages3
    JournalInternational Journal of Infectious Diseases
    Publication statusPublished - 2018 Oct

    Bibliographical note

    Funding Information:
    This study was supported by Intramural Funds ( 4834-303-210 ) from the Korea Centers for Disease Control and Prevention. The H5N6 isolates, A/duck/Korea/ES2/2016(H5N6), were kindly provided by the Avian Disease Division of the Animal and Plant Quarantine Agency in the Republic of Korea. We thank Benjamin J. Cowling at the WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China for his helpful discussions.

    Publisher Copyright:
    © 2018 The Author(s)


    • Avian influenza
    • H5N6
    • Korea
    • Poultry
    • Transmission

    ASJC Scopus subject areas

    • Microbiology (medical)
    • Infectious Diseases


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