Serum levels of marine-derived n-3 fatty acids in Icelanders, Japanese, Koreans, and Americans-A descriptive epidemiologic study

Akira Sekikawa, Laufey Steingrimsdottir, Hirotsugu Ueshima, Chol Shin, J. David Curb, Rhobert W. Evans, Alda M. Hauksdottir, Aya Kadota, Jina Choo, Kamal Masaki, Bolli Thorsson, Lenore J. Launer, Melisa E. Garcia, Hiroshi Maegawa, Bradley J. Willcox, Gudny Eiriksdottir, Akira Fujiyoshi, Katsuyuki Miura, Tamara B. Harris, Lewis H. KullerVilmundur Gudnason

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)


In the 1990s Iceland and Japan were known as countries with high fish consumption whereas coronary heart disease (CHD) mortality in Iceland was high and that in Japan was low among developed countries. We described recent data fish consumption and CHD mortality from publicly available data. We also measured CHD risk factors and serum levels of marine-derived n-3 and other fatty acids from population-based samples of 1324 men in Iceland, Japan, South Korea, and the US. CHD mortality in men in Iceland was almost 3 times as high as that in Japan and South Korea. Generally, a profile of CHD risk factors in Icelanders compared to Japanese was more favorable. Serum marine-derived n-3 fatty acids in Iceland were significantly lower than in Japan and South Korea but significantly higher than in the US.

Original languageEnglish
Pages (from-to)11-16
Number of pages6
JournalProstaglandins Leukotrienes and Essential Fatty Acids
Issue number1
Publication statusPublished - 2012 Jul

Bibliographical note

Funding Information:
This research was funded by the Icelandic Heart Association, Iceland, the Korea Centers for Disease Control and Prevention, Ministry for Health and Welfare 2004-E71001–00, 2005-E71001-00 , Korea , R01HL68200, R01HL071561, and N01AG12100 , from the National Institutes of Health, the USA , B 16790335 and A 13307016 from the Japanese Ministry of Education, Culture, Sports, Science and Technology, Japan, and partly supported by the Intramural research program of the National Institutes of Health, National Institute on Aging, the USA.


  • Coronary heart disease
  • Descriptive epidemiologic study
  • Docosahexaenoic acid
  • Eicosapentaenoic acid
  • N-3 fatty acids

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology


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