Abstract
The bacilli Calmette-Guérin (BCG) Tokyo-172 strain was considered to exhibit good protective efficacy with a low rate of unfavorable side effects. However, we describe a rare case of BCG osteomyelitis developed in an immunocompetent host who was given with BCG Tokyo-172 vaccine on the left upper arm by multipuncture method. A 9-month-old girl presented with progressive inability to move her right elbow and had radiographic evidence of septic elbow combined with osteomyelitis of right distal humerus. A biopsy from the site revealed chronic caseating granulomatous inflammation, positive for BCG Tokyo-172 strain on the multiplex polymerase chain reaction. The child had to undergo second surgical debridements and oral antituberculosis chemotherapy. There were no sequelae after 2 yr of follow-up. This complication, although uncommon, should be considered in the appropriate clinical setting.
Original language | English |
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Pages (from-to) | 221-224 |
Number of pages | 4 |
Journal | Journal of Korean medical science |
Volume | 27 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2012 |
Externally published | Yes |
Keywords
- Bacilli calmette-guérin vaccination
- Complication
- Osteomyelitis
ASJC Scopus subject areas
- Medicine(all)