Objectives The aim of this study was to investigate whether osteoporosis is more prevalent in elderly Korean people who have had a stroke and whether the association differs by sex. Study design A total of 3806 elderly subjects (1951 men and 1855 women) from the Korea National Health and Nutrition Examination Survey were included in this study. Stroke history was determined by self-administered questionnaire. Bone mineral density (BMD) was measured at the lumbar spine, total hip, and neck of the femur using dual-energy X-ray absorptiometry. It was categorized as normal, osteopenia, or osteoporosis. Results In men who had had a stroke, the prevalence of osteoporosis was greater than that of both osteopenia and normal BMD, and the prevalence of osteopenia was greater than that of normal BMD (p < 0.001). However, there were no significant differences in BMD level among women who had had a stroke. Men who had had a stroke undertook less vigorous exercise and moderate-or-vigorous exercise than did men who had not had a stroke (p = 0.002 and 0.030, respectively). After adjusting for all covariates, the mean BMD at the lumbar spine, total hip and neck of the femur was lower in men who had had a stroke than in men who had not (p = 0.034, 0.002, and 0.005, respectively). There were no significant differences in mean BMD at any of the three sites between women who had and women who had not had a stroke. Conclusion Men who have had a stroke have a higher prevalence of osteopenia and osteoporosis, and have lower BMD at the total hip and femur neck than men who have not had a stroke.
Bibliographical noteFunding Information:
The research protocol was approved by the Korean Ministry of Health and Welfare and administered according to the Ethical Principles for Medical Research Involving Human Subjects by the Helsinki Declaration (2008-04EXP-01-C, 2009-01CON-03-2C, and 2010-02CON-21-C). All subjects provided informed written consent.
© 2016 Elsevier Ireland Ltd
- Bone mineral density
- Korean National Health and Nutrition Examination Survey
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Obstetrics and Gynaecology