Abstract
A one-pot conversion of meso-cyclic anhydrides with alcoholysis in diethyl ether using SGS-(DHQ)2AQN 4, a silica gel-supported chiral catalyst, into the corresponding desymmetrized mono ester acids was achieved with enantiomeric excesses of up to 84% under mild and efficient conditions.
Original language | English |
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Pages (from-to) | 3301-3304 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 45 |
Issue number | 16 |
DOIs | |
Publication status | Published - 2004 Apr 12 |
Keywords
- (DHQ)AQN
- Catalyst immobilization
- Desymmetrization
- SGS-(DHQ)AQN
- meso-Cyclic anhydride
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry