Simultaneous acquisition of ultrasound and Gamma signals with a single-channel readout

Muhammad Nasir Ullah; Yuseung Park; Gyeong Beom Kim; Chanho Kim; Chansun Park; Hojong Choi; Jung Yeol Yeom

doi:10.3390/s21041048

Simultaneous acquisition of ultrasound and Gamma signals with a single-channel readout

Muhammad Nasir Ullah, Yuseung Park, Gyeong Beom Kim, Chanho Kim, Chansun Park, Hojong Choi, Jung Yeol Yeom

School of Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

We propose an integrated front-end data acquisition circuit for a hybrid ultrasound (US)-gamma probe. The proposed circuit consists of three main parts: (1) a preamplifier for the gamma probe, (2) a preprocessing analog circuit for the US, and (3) a digitally controlled analog switch. By exploiting the long idle time of the US system, an analog switch can be used to acquire data of both systems using a single output channel simultaneously. On the nuclear medicine (NM) gamma probe side, energy resolutions of 18.4% and 17.5% were acquired with the standalone system and with the proposed switching circuit, respectively, when irradiated with a Co-57 radiation source. Similarly, signal-to-noise ratios of 14.89 and 13.12 dB were achieved when US echo signals were acquired with the standalone system and with the proposed switching circuit, respectively. Lastly, a combined US-gamma probe was used to scan a glass target and a sealed radiation source placed in a water tank. The results confirmed that, by using a hybrid US-gamma probe system, it is possible to distinguish between the two objects and acquire structural information (ultrasound) alongside molecular information (gamma radiation source).

Original language	English
Article number	1048
Pages (from-to)	1-12
Number of pages	12
Journal	Sensors (Switzerland)
Volume	21
Issue number	4
DOIs	https://doi.org/10.3390/s21041048
Publication status	Published - 2021 Feb 2

Bibliographical note

Funding Information:
This research was funded by the National Research Foundation of Korea (NRF) grant funded by the government (MSIT) (No. 2020R1A2C2007376, No. 2020M2A8A4023713, and No. 2020R1A2C4001606) and the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) funded by the Ministry of Health & Welfare, Republic of Korea (HI17C0654).

Funding Information:
Funding: This research was funded by the National Research Foundation of Korea (NRF) grant funded by the government (MSIT) (No. 2020R1A2C2007376, No. 2020M2A8A4023713, and No. 2020R1A2C4001606) and the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) funded by the Ministry of Health & Welfare, Republic of Korea (HI17C0654).

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

Gamma probe
Hybrid systems
Nuclear medicine (NM)
Silicon photomultiplier (SiPM)
Ultrasound probe

ASJC Scopus subject areas

Analytical Chemistry
Information Systems
Atomic and Molecular Physics, and Optics
Biochemistry
Instrumentation
Electrical and Electronic Engineering

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10.3390/s21041048

Cite this

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title = "Simultaneous acquisition of ultrasound and Gamma signals with a single-channel readout",

abstract = "We propose an integrated front-end data acquisition circuit for a hybrid ultrasound (US)-gamma probe. The proposed circuit consists of three main parts: (1) a preamplifier for the gamma probe, (2) a preprocessing analog circuit for the US, and (3) a digitally controlled analog switch. By exploiting the long idle time of the US system, an analog switch can be used to acquire data of both systems using a single output channel simultaneously. On the nuclear medicine (NM) gamma probe side, energy resolutions of 18.4% and 17.5% were acquired with the standalone system and with the proposed switching circuit, respectively, when irradiated with a Co-57 radiation source. Similarly, signal-to-noise ratios of 14.89 and 13.12 dB were achieved when US echo signals were acquired with the standalone system and with the proposed switching circuit, respectively. Lastly, a combined US-gamma probe was used to scan a glass target and a sealed radiation source placed in a water tank. The results confirmed that, by using a hybrid US-gamma probe system, it is possible to distinguish between the two objects and acquire structural information (ultrasound) alongside molecular information (gamma radiation source).",

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author = "Ullah, {Muhammad Nasir} and Yuseung Park and Kim, {Gyeong Beom} and Chanho Kim and Chansun Park and Hojong Choi and Yeom, {Jung Yeol}",

note = "Funding Information: This research was funded by the National Research Foundation of Korea (NRF) grant funded by the government (MSIT) (No. 2020R1A2C2007376, No. 2020M2A8A4023713, and No. 2020R1A2C4001606) and the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) funded by the Ministry of Health & Welfare, Republic of Korea (HI17C0654). Funding Information: Funding: This research was funded by the National Research Foundation of Korea (NRF) grant funded by the government (MSIT) (No. 2020R1A2C2007376, No. 2020M2A8A4023713, and No. 2020R1A2C4001606) and the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) funded by the Ministry of Health & Welfare, Republic of Korea (HI17C0654). Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

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AU - Park, Chansun

AU - Choi, Hojong

AU - Yeom, Jung Yeol

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PY - 2021/2/2

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N2 - We propose an integrated front-end data acquisition circuit for a hybrid ultrasound (US)-gamma probe. The proposed circuit consists of three main parts: (1) a preamplifier for the gamma probe, (2) a preprocessing analog circuit for the US, and (3) a digitally controlled analog switch. By exploiting the long idle time of the US system, an analog switch can be used to acquire data of both systems using a single output channel simultaneously. On the nuclear medicine (NM) gamma probe side, energy resolutions of 18.4% and 17.5% were acquired with the standalone system and with the proposed switching circuit, respectively, when irradiated with a Co-57 radiation source. Similarly, signal-to-noise ratios of 14.89 and 13.12 dB were achieved when US echo signals were acquired with the standalone system and with the proposed switching circuit, respectively. Lastly, a combined US-gamma probe was used to scan a glass target and a sealed radiation source placed in a water tank. The results confirmed that, by using a hybrid US-gamma probe system, it is possible to distinguish between the two objects and acquire structural information (ultrasound) alongside molecular information (gamma radiation source).

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Simultaneous acquisition of ultrasound and Gamma signals with a single-channel readout

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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