Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

Hyangah Chon; Sangyeop Lee; Soo Young Yoon; Soo Ik Chang; Dong Woo Lim; Jaebum Choo

doi:10.1039/c1cc15707h

Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

Hyangah Chon, Sangyeop Lee, Soo Young Yoon, Soo Ik Chang, Dong Woo Lim, Jaebum Choo

Research output: Contribution to journal › Article › peer-review

118 Citations (Scopus)

Abstract

A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.

Original language	English
Pages (from-to)	12515-12517
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	46
DOIs	https://doi.org/10.1039/c1cc15707h
Publication status	Published - 2011 Dec 14

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1039/c1cc15707h

Cite this

@article{363d9a877cb642869dcf323131d81a69,

title = "Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes",

abstract = "A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.",

author = "Hyangah Chon and Sangyeop Lee and Yoon, {Soo Young} and Chang, {Soo Ik} and Lim, {Dong Woo} and Jaebum Choo",

year = "2011",

month = dec,

day = "14",

doi = "10.1039/c1cc15707h",

language = "English",

volume = "47",

pages = "12515--12517",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "46",

}

TY - JOUR

T1 - Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

AU - Chon, Hyangah

AU - Lee, Sangyeop

AU - Yoon, Soo Young

AU - Chang, Soo Ik

AU - Lim, Dong Woo

AU - Choo, Jaebum

PY - 2011/12/14

Y1 - 2011/12/14

N2 - A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.

AB - A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.

UR - http://www.scopus.com/inward/record.url?scp=81255210336&partnerID=8YFLogxK

U2 - 10.1039/c1cc15707h

DO - 10.1039/c1cc15707h

M3 - Article

C2 - 22027811

AN - SCOPUS:81255210336

SN - 1359-7345

VL - 47

SP - 12515

EP - 12517

JO - Chemical Communications

JF - Chemical Communications

IS - 46

ER -

Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this