Single cardiac cycle three-dimensional intracoronary optical coherence tomography

Tae Shik Kim, Hyun Sang Park, Sun Joo Jang, Joon Woo Song, Han Saem Cho, Sunwon Kim, Brett E. Bouma, Jin Won Kim, Wang Yuhl Oh

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

While high-speed intracoronary optical coherence tomography (OCT) provides three-dimensional (3D) visualization of coronary arteries in vivo, imaging speeds remain insufficient to avoid motion artifacts induced by heartbeat, limiting the clinical utility of OCT. In this paper, we demonstrate development of a high-speed intracoronary OCT system (frame rate: 500 frames/s, pullback speed: 100 mm/s) along with prospective electrocardiogram (ECG) triggering technology, which enabled volumetric imaging of long coronary segments within a single cardiac cycle (70 mm pullback in 0.7 s) with minimal cardiac motion artifact. This technology permitted detailed visualization of 3D architecture of the coronary arterial wall of a swine in vivo and fine structure of the implanted stent.

Original languageEnglish
Article number267999
Pages (from-to)4847-4858
Number of pages12
JournalBiomedical Optics Express
Volume7
Issue number12
DOIs
Publication statusPublished - 2016 Dec 1
Externally publishedYes

Bibliographical note

Funding Information:
This study was supported by the National Research Foundation of Korea (grant 2010-0017465 and grant 2012R1A2A2A04046108), the Ministry of Health and Welfare of Korea (grant HI15C0001), and the National Institutes of Health (grant P41 EB015903).

Publisher Copyright:
© 2016 Optical Society of America.

Keywords

  • Endoscopic imaging
  • Medical and biological imaging
  • Optical coherence tomography

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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