Single-Molecule Methods to Study Z-DNA Mechanics and Dynamics

Hae Jun Jung, Beom Hyeon Park, Sook Ho Kim, Seok Cheol Hong

Research output: Chapter in Book/Report/Conference proceedingChapter


Single-molecule methods are powerful in revealing physical and mechanobiological details about biological phenomena. Here, we describe the single-molecule methods applied to study mechanical properties of Z-DNA and dynamics of the B–Z transition.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Number of pages19
Publication statusPublished - 2023

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Bibliographical note

Funding Information:
This work was supported by NRF-2019R1A2C1089808 and IBS-R023-D1.

Publisher Copyright:
© 2023, The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.


  • B–Z transition
  • Magnetic tweezers
  • Real-time dynamics
  • Single-molecule FRET
  • Z-DNA mechanics

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


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