Single-Molecule Methods to Study Z-DNA Mechanics and Dynamics

  • Hae Jun Jung
  • , Beom Hyeon Park
  • , Sook Ho Kim*
  • , Seok Cheol Hong
  • *Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2 Citations (Scopus)

    Abstract

    Single-molecule methods are powerful in revealing physical and mechanobiological details about biological phenomena. Here, we describe the single-molecule methods applied to study mechanical properties of Z-DNA and dynamics of the B–Z transition.

    Original languageEnglish
    Title of host publicationMethods in Molecular Biology
    PublisherHumana Press Inc.
    Pages85-103
    Number of pages19
    DOIs
    Publication statusPublished - 2023

    Publication series

    NameMethods in Molecular Biology
    Volume2651
    ISSN (Print)1064-3745
    ISSN (Electronic)1940-6029

    Bibliographical note

    Funding Information:
    This work was supported by NRF-2019R1A2C1089808 and IBS-R023-D1.

    Publisher Copyright:
    © 2023, The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

    Keywords

    • B–Z transition
    • Magnetic tweezers
    • Real-time dynamics
    • Single-molecule FRET
    • Z-DNA mechanics

    ASJC Scopus subject areas

    • Molecular Biology
    • Genetics

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