Skin absorption potential of ZnO nanoparticles

Sun Yae Kim; Sang Hoon Jeong; Eun Young Lee; Yoon Hee Park; Hyun Cheol Bae; Yeon Sue Jang; Eun Ho Maeng; Meyoung Kon Kim; Sang Wook Son

doi:10.1007/s13530-011-0100-7

Skin absorption potential of ZnO nanoparticles

Sun Yae Kim, Sang Hoon Jeong, Eun Young Lee, Yoon Hee Park, Hyun Cheol Bae, Yeon Sue Jang, Eun Ho Maeng, Meyoung Kon Kim, Sang Wook Son

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

In spite of widely use of zinc oxide (ZnO) nanoparticles (NPs) in cosmetic industry and in our daily lives, there are insufficient data on their potential of skin absorption. This study was conducted to investigate the potential of skin absorption induced by ZnO NPs, especially influences of the surface charge and different particle size. Assessment of potential of skin absorption was estimated using 3D EpiDerm™ model (EPI-200) as human skin equivalent model (HSEM). This study demonstrated no evidence of significant penetration of ZnO NPs into the HSEM after 24 h exposure.

Original language	English
Pages (from-to)	258-261
Number of pages	4
Journal	Toxicology and Environmental Health Sciences
Volume	3
Issue number	4
DOIs	https://doi.org/10.1007/s13530-011-0100-7
Publication status	Published - 2011 Dec

Keywords

3D EpiDerm™ model (EPI-200)
Absorption
Skin
ZnO

ASJC Scopus subject areas

Toxicology
Health, Toxicology and Mutagenesis

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10.1007/s13530-011-0100-7

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title = "Skin absorption potential of ZnO nanoparticles",

abstract = "In spite of widely use of zinc oxide (ZnO) nanoparticles (NPs) in cosmetic industry and in our daily lives, there are insufficient data on their potential of skin absorption. This study was conducted to investigate the potential of skin absorption induced by ZnO NPs, especially influences of the surface charge and different particle size. Assessment of potential of skin absorption was estimated using 3D EpiDerm{\texttrademark} model (EPI-200) as human skin equivalent model (HSEM). This study demonstrated no evidence of significant penetration of ZnO NPs into the HSEM after 24 h exposure.",

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author = "Kim, {Sun Yae} and Jeong, {Sang Hoon} and Lee, {Eun Young} and Park, {Yoon Hee} and Bae, {Hyun Cheol} and Jang, {Yeon Sue} and Maeng, {Eun Ho} and Kim, {Meyoung Kon} and Son, {Sang Wook}",

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language = "English",

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pages = "258--261",

journal = "Toxicology and Environmental Health Sciences",

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publisher = "Korean Society of Environmental Risk Assessment and Health Science",

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T1 - Skin absorption potential of ZnO nanoparticles

AU - Kim, Sun Yae

AU - Jeong, Sang Hoon

AU - Lee, Eun Young

AU - Park, Yoon Hee

AU - Bae, Hyun Cheol

AU - Jang, Yeon Sue

AU - Maeng, Eun Ho

AU - Kim, Meyoung Kon

AU - Son, Sang Wook

PY - 2011/12

Y1 - 2011/12

N2 - In spite of widely use of zinc oxide (ZnO) nanoparticles (NPs) in cosmetic industry and in our daily lives, there are insufficient data on their potential of skin absorption. This study was conducted to investigate the potential of skin absorption induced by ZnO NPs, especially influences of the surface charge and different particle size. Assessment of potential of skin absorption was estimated using 3D EpiDerm™ model (EPI-200) as human skin equivalent model (HSEM). This study demonstrated no evidence of significant penetration of ZnO NPs into the HSEM after 24 h exposure.

AB - In spite of widely use of zinc oxide (ZnO) nanoparticles (NPs) in cosmetic industry and in our daily lives, there are insufficient data on their potential of skin absorption. This study was conducted to investigate the potential of skin absorption induced by ZnO NPs, especially influences of the surface charge and different particle size. Assessment of potential of skin absorption was estimated using 3D EpiDerm™ model (EPI-200) as human skin equivalent model (HSEM). This study demonstrated no evidence of significant penetration of ZnO NPs into the HSEM after 24 h exposure.

KW - 3D EpiDerm™ model (EPI-200)

KW - Absorption

KW - Skin

KW - ZnO

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EP - 261

JO - Toxicology and Environmental Health Sciences

JF - Toxicology and Environmental Health Sciences

IS - 4

ER -

Skin absorption potential of ZnO nanoparticles

Abstract

Keywords

ASJC Scopus subject areas

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