Skin microrelief profiles as a cutaneous aging index

Dai Hyun Kim, Yeon Seung Rhyu, Hyo Hyun Ahn, Eenjun Hwang, Chang Sub Uhm

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


An objective measurement of cutaneous topographical information is important for quantifying the degree of skin aging. Our aim was to improve methods for measuring microrelief patterns using a three-dimensional analysis based on silicone replicas and scanning electron microscope (SEM). Another objective was to compare the results with those obtained using a two-dimensional analysis method based on dermoscopy. Silicone replicas were obtained from forearms,dorsum of the hands and fingers of 51 volunteers. Cutaneous profiles obtained by SEM with silicone replicas showed more consistent correlations with age than data obtained by dermoscopy. This indicates the advantage of three-dimensional topography analysis using silicone replicas and SEM over the widely used dermoscopic assessment. The cutaneous age was calculated using stepwise linear regression,and the result was 57.40-9.47 × (number of furrows on dorsum of the hand) × (width of furrows on dorsum of the hand).

Original languageEnglish
Pages (from-to)407-414
Number of pages8
Issue number5
Publication statusPublished - 2016 Oct 1

Bibliographical note

Publisher Copyright:
© The Author 2016. Published by Oxford University Press on behalf of The Japanese Society of Microscopy. All rights reserved.


  • Dermoscopy
  • Microrelief
  • Scanning electron microscopy
  • Silicone replica
  • Skin aging
  • Three-dimensional topography analysis

ASJC Scopus subject areas

  • Structural Biology
  • Instrumentation
  • Radiology Nuclear Medicine and imaging


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