Sodium-ion-selective two-photon fluorescent probe for in vivo imaging

Mi Kyung Kim; Chang Su Lim; Jong Tae Hong; Ji Hee Han; Hye Young Jang; Hwan Myung Kim; Bong Rae Cho

doi:10.1002/anie.200904835

Sodium-ion-selective two-photon fluorescent probe for in vivo imaging

Mi Kyung Kim, Chang Su Lim, Jong Tae Hong, Ji Hee Han, Hye Young Jang, Hwan Myung Kim, Bong Rae Cho

Research output: Contribution to journal › Article › peer-review

103 Citations (Scopus)

Abstract

"Chemical Equation Presented" Two photons are better than one: A two-photon probe (ANa1, see picture) shows strong twophoton fluorescence enhancement In response to Na⁺ and a dissociation constant (K _d^l) of (26±2) mM in the cell. It can be easily loaded into the cells and can selectively detect intracellular free Na ⁺ in live cells and living tissues at a depth of 100-200 μm for a long period of time.

Original language	English
Pages (from-to)	364-367
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	2
DOIs	https://doi.org/10.1002/anie.200904835
Publication status	Published - 2010 Jan 8

Keywords

Fluorescent probes
Live tissue
Sodium
Two-photon microscopy

ASJC Scopus subject areas

Catalysis
General Chemistry

Access to Document

10.1002/anie.200904835

Cite this

@article{89c318e05fd147cd86bfa1e17f9baaa9,

title = "Sodium-ion-selective two-photon fluorescent probe for in vivo imaging",

abstract = "{"}Chemical Equation Presented{"} Two photons are better than one: A two-photon probe (ANa1, see picture) shows strong twophoton fluorescence enhancement In response to Na+ and a dissociation constant (K dl) of (26±2) mM in the cell. It can be easily loaded into the cells and can selectively detect intracellular free Na + in live cells and living tissues at a depth of 100-200 μm for a long period of time.",

keywords = "Fluorescent probes, Live tissue, Sodium, Two-photon microscopy",

author = "Kim, {Mi Kyung} and Lim, {Chang Su} and Hong, {Jong Tae} and Han, {Ji Hee} and Jang, {Hye Young} and Kim, {Hwan Myung} and Cho, {Bong Rae}",

year = "2010",

month = jan,

day = "8",

doi = "10.1002/anie.200904835",

language = "English",

volume = "49",

pages = "364--367",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "2",

}

TY - JOUR

T1 - Sodium-ion-selective two-photon fluorescent probe for in vivo imaging

AU - Kim, Mi Kyung

AU - Lim, Chang Su

AU - Hong, Jong Tae

AU - Han, Ji Hee

AU - Jang, Hye Young

AU - Kim, Hwan Myung

AU - Cho, Bong Rae

PY - 2010/1/8

Y1 - 2010/1/8

N2 - "Chemical Equation Presented" Two photons are better than one: A two-photon probe (ANa1, see picture) shows strong twophoton fluorescence enhancement In response to Na+ and a dissociation constant (K dl) of (26±2) mM in the cell. It can be easily loaded into the cells and can selectively detect intracellular free Na + in live cells and living tissues at a depth of 100-200 μm for a long period of time.

AB - "Chemical Equation Presented" Two photons are better than one: A two-photon probe (ANa1, see picture) shows strong twophoton fluorescence enhancement In response to Na+ and a dissociation constant (K dl) of (26±2) mM in the cell. It can be easily loaded into the cells and can selectively detect intracellular free Na + in live cells and living tissues at a depth of 100-200 μm for a long period of time.

KW - Fluorescent probes

KW - Live tissue

KW - Sodium

KW - Two-photon microscopy

UR - http://www.scopus.com/inward/record.url?scp=73349108476&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=73349108476&partnerID=8YFLogxK

U2 - 10.1002/anie.200904835

DO - 10.1002/anie.200904835

M3 - Article

C2 - 19998298

AN - SCOPUS:73349108476

SN - 1433-7851

VL - 49

SP - 364

EP - 367

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 2

ER -

Sodium-ion-selective two-photon fluorescent probe for in vivo imaging

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this