Sodium-ion-selective two-photon fluorescent probe for in vivo imaging

Mi Kyung Kim; Chang Su Lim; Jong Tae Hong; Ji Hee Han; Hye Young Jang; Hwan Myung Kim; Bong Rae Cho

doi:10.1002/anie.200904835

Sodium-ion-selective two-photon fluorescent probe for in vivo imaging

Mi Kyung Kim
, Chang Su Lim
, Jong Tae Hong
, Ji Hee Han
, Hye Young Jang
, Hwan Myung Kim
, Bong Rae Cho

Research output: Contribution to journal › Article › peer-review

103 Citations (Scopus)

Abstract

"Chemical Equation Presented" Two photons are better than one: A two-photon probe (ANa1, see picture) shows strong twophoton fluorescence enhancement In response to Na⁺ and a dissociation constant (K _d^l) of (26±2) mM in the cell. It can be easily loaded into the cells and can selectively detect intracellular free Na ⁺ in live cells and living tissues at a depth of 100-200 μm for a long period of time.

Original language	English
Pages (from-to)	364-367
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	2
DOIs	https://doi.org/10.1002/anie.200904835
Publication status	Published - 2010 Jan 8

Keywords

Fluorescent probes
Live tissue
Sodium
Two-photon microscopy

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.200904835

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abstract = "{"}Chemical Equation Presented{"} Two photons are better than one: A two-photon probe (ANa1, see picture) shows strong twophoton fluorescence enhancement In response to Na+ and a dissociation constant (K dl) of (26±2) mM in the cell. It can be easily loaded into the cells and can selectively detect intracellular free Na + in live cells and living tissues at a depth of 100-200 μm for a long period of time.",

keywords = "Fluorescent probes, Live tissue, Sodium, Two-photon microscopy",

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AU - Kim, Mi Kyung

AU - Lim, Chang Su

AU - Hong, Jong Tae

AU - Han, Ji Hee

AU - Jang, Hye Young

AU - Kim, Hwan Myung

AU - Cho, Bong Rae

PY - 2010/1/8

Y1 - 2010/1/8

N2 - "Chemical Equation Presented" Two photons are better than one: A two-photon probe (ANa1, see picture) shows strong twophoton fluorescence enhancement In response to Na+ and a dissociation constant (K dl) of (26±2) mM in the cell. It can be easily loaded into the cells and can selectively detect intracellular free Na + in live cells and living tissues at a depth of 100-200 μm for a long period of time.

AB - "Chemical Equation Presented" Two photons are better than one: A two-photon probe (ANa1, see picture) shows strong twophoton fluorescence enhancement In response to Na+ and a dissociation constant (K dl) of (26±2) mM in the cell. It can be easily loaded into the cells and can selectively detect intracellular free Na + in live cells and living tissues at a depth of 100-200 μm for a long period of time.

KW - Fluorescent probes

KW - Live tissue

KW - Sodium

KW - Two-photon microscopy

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UR - https://www.scopus.com/pages/publications/73349108476#tab=citedBy

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JO - Angewandte Chemie - International Edition

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ER -

Sodium-ion-selective two-photon fluorescent probe for in vivo imaging

Abstract

Keywords

ASJC Scopus subject areas

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