Soft, Long-Lived, Bioresorbable Electronic Surgical Mesh with Wireless Pressure Monitor and On-Demand Drug Delivery

Rajaram Kaveti, Joong Hoon Lee, Joong Kee Youn, Tae Min Jang, Won Bae Han, Seung Min Yang, Jeong Woong Shin, Gwan Jin Ko, Dong Je Kim, Sungkeun Han, Heeseok Kang, Amay J. Bandodkar, Hyun Young Kim, Suk Won Hwang

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Current research in the area of surgical mesh implants is somewhat limited to traditional designs and synthesis of various mesh materials, whereas meshes with multiple functions may be an effective approach to address long-standing challenges including postoperative complications. Herein, a bioresorbable electronic surgical mesh is presented that offers high mechanical strength over extended timeframes, wireless post-operative pressure monitoring, and on-demand drug delivery for the restoration of tissue structure and function. The study of materials and mesh layouts provides a wide range of tunability of mechanical and biochemical properties. Dissolvable dielectric composite with porous structure in a pyramidal shape enhances sensitivity of a wireless capacitive pressure sensor, and resistive microheaters integrated with inductive coils provide thermo-responsive drug delivery system for an antibacterial agent. In vivo evaluations demonstrate reliable, long-lived operation, and effective treatment for abdominal hernia defects, by clear evidence of suppressed complications such as adhesion formation and infections.

Original languageEnglish
Article number2307391
JournalAdvanced Materials
Volume36
Issue number11
DOIs
Publication statusPublished - 2024 Mar 14

Bibliographical note

Publisher Copyright:
© 2023 Wiley-VCH GmbH.

Keywords

  • biodegradable elastomer
  • hernia repair
  • surgical mesh
  • transient electronics
  • wireless pressure sensor

ASJC Scopus subject areas

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering

Fingerprint

Dive into the research topics of 'Soft, Long-Lived, Bioresorbable Electronic Surgical Mesh with Wireless Pressure Monitor and On-Demand Drug Delivery'. Together they form a unique fingerprint.

Cite this