Spontaneously healed asymptomatic pulmonary tuberculosis: Prevalence of airflow obstruction, and correlation between high-resolution CT findings and pulmonary function tests

Ki Yeol Lee, Chol Shin, Jung Bok Lee, Eun Young Kang, Yu Whan Oh, Bo Kyung Je, Ji Young Choo, Dae Wui Yoon, Pyong Kon Cho

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)

    Abstract

    RATIONALE AND OBJECTIVES: We investigated the relationships between spontaneously healed asymptomatic pulmonary tuberculosis (SHAPTB), airflow obstruction (AFO), and high-resolution computed tomography (HRCT) findings. MATERIALS AND METHODS: We selected 82 participants with SHAPTB diagnosed by interferon-γ release assay and 8044 with normal chest radiographs (CXR). We applied a CT scoring system for the extent of tuberculous sequelae to correlate the HRCT findings with pulmonary function test. We compared the AFO prevalence between subjects with and without SHAPTB. RESULTS: The subjects with SHAPTB diagnosed by interferon-γ release assay had a significantly higher prevalence of AFO (13.4% [11/82]) than those with normal CXR (7.4% [595/8044]). The important HRCT findings that correlated with AFO were the number of lung segments with TB sequelae and the CT score for emphysema. CONCLUSION: The subjects with SHAPTB had a higher AFO prevalence than those with normal CXR, and the important HRCT findings correlated with AFO were the extent of tuberculous sequelae and emphysema.

    Original languageEnglish
    Pages (from-to)528-533
    Number of pages6
    JournalJournal of Computer Assisted Tomography
    Volume36
    Issue number5
    DOIs
    Publication statusPublished - 2012

    Keywords

    • airway obstruction
    • computed tomography
    • prevalence
    • respiratory function test
    • tomography
    • tuberculosis

    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging

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