Staring at protein-surfactant interactions: Fundamental approaches and comparative evaluation of their combinations - A review

Yan Li, Jae Seung Lee

Research output: Contribution to journalReview articlepeer-review

32 Citations (Scopus)

Abstract

Protein-surfactant interactions have been explored for decades owing to their widespread application in the pharmaceutical, food, and cosmetics industries and their importance to biochemical systems. However, they require further study owing to their compositional complexity and the innate limitations of current analytical approaches. In this review, we briefly introduce a series of individual approaches used for the qualitative and quantitative investigation of protein-surfactant interactions, including absorbance- or emission-based spectroscopy, scattering-based spectroscopy, mass spectrometry, calorimetry, computation and microscopy. More importantly, we then compare and evaluate various combinations of these approaches and provide comprehensive critical assessments and comments regarding their application to the advanced study of protein-surfactant interactions at the molecular level.

Original languageEnglish
Pages (from-to)18-39
Number of pages22
JournalAnalytica Chimica Acta
Volume1063
DOIs
Publication statusPublished - 2019 Jul 31

Bibliographical note

Funding Information:
This work was supported by the NRF funded by the Korean government, MSIP (NRF2015M3A9D7031015, NRF-2018R1A1A1A05079384 and NRF-2016R1A5A1010148).

Funding Information:
This work was supported by the NRF funded by the Korean government, MSIP (NRF 2015M3A9D7031015 , NRF- 2018R1A1A1A05079384 and NRF- 2016R1A5A1010148 ).

Publisher Copyright:
© 2019 Elsevier B.V.

Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.

Keywords

  • Calorimetry
  • Combinations of analytical approaches
  • Computation
  • Microscopy
  • Protein-surfactant interactions
  • Spectroscopy and spectrometry

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy

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