Protein-surfactant interactions have been explored for decades owing to their widespread application in the pharmaceutical, food, and cosmetics industries and their importance to biochemical systems. However, they require further study owing to their compositional complexity and the innate limitations of current analytical approaches. In this review, we briefly introduce a series of individual approaches used for the qualitative and quantitative investigation of protein-surfactant interactions, including absorbance- or emission-based spectroscopy, scattering-based spectroscopy, mass spectrometry, calorimetry, computation and microscopy. More importantly, we then compare and evaluate various combinations of these approaches and provide comprehensive critical assessments and comments regarding their application to the advanced study of protein-surfactant interactions at the molecular level.
Bibliographical noteFunding Information:
This work was supported by the NRF funded by the Korean government, MSIP (NRF2015M3A9D7031015, NRF-2018R1A1A1A05079384 and NRF-2016R1A5A1010148).
This work was supported by the NRF funded by the Korean government, MSIP (NRF 2015M3A9D7031015 , NRF- 2018R1A1A1A05079384 and NRF- 2016R1A5A1010148 ).
© 2019 Elsevier B.V.
Copyright 2019 Elsevier B.V., All rights reserved.
- Combinations of analytical approaches
- Protein-surfactant interactions
- Spectroscopy and spectrometry
ASJC Scopus subject areas
- Analytical Chemistry
- Environmental Chemistry