Abstract
2,3-Butanediol is an attractive product for biorefinery due to its various applications and industrial potential. Enterobacter aerogenes is also considered as a major 2,3-butanediol producer. This study is intended to enhance the production of 2,3-butanediol with addition of acetate into the culture media using E. aerogenes ATCC 29007 and to determine the mechanism of improved 2,3-butanediol production. 2,3-Butanediol production was increased by 34.2% with the addition of acetate in batch culture compared to that without acetate in 130 g/L of glucose. This increase was caused by buffering effects and upregulation of the transcription levels of genes involved in 2,3-butanediol production through acetate addition.
Original language | English |
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Pages (from-to) | 1904-1910 |
Number of pages | 7 |
Journal | Process Biochemistry |
Volume | 51 |
Issue number | 12 |
DOIs | |
Publication status | Published - 2016 Dec 1 |
Keywords
- 2,3-Butanediol
- Acetate
- Enterobacter aerogenes
- Fermentation
- Transcriptional regulation
ASJC Scopus subject areas
- Bioengineering
- Biochemistry
- Applied Microbiology and Biotechnology