Stratus OCT image analysis with spectral-domain OCT (Topcon 3D OCT Viewer)

Aims: To assess the accuracy of the Topcon 3D OCT Viewer in analysing Stratus OCT data. Methods: Randomly selected fast macular thickness map protocol optical coherence tomography (OCT) raw data were exported from the Stratus OCT database and imported into and analysed with the Topcon 3D OCT Viewer. The segmentation error (SE) rates and scores were compared between the two programs. Differences in the retinal thickness between the two programs were measured in both the SE (-) group and the SE (+) group. Results: 356 eyes were analysed. The SE rate and mean SE score were significantly lower with the Topcon 3D OCT Viewer than with Stratus OCT ((30.9% (110/356) vs 38.2% (136/356), p=0.011; 0.33±0.59 vs 0.48±0.96, p=0.003), respectively). In the SE (e) group, the mean of the differences between the two programs was -2.79 μm (p<0.001) in the central 1 mm zone of the nine ETDRS areas and 1.49 mm (p=0.152) for the automated centre point thickness. Conclusions The Topcon 3D OCT Viewer analysed Stratus OCT data very well and displayed better segmentation performance. The Topcon 3D OCT Viewer program can be used interchangeably for the measurement of macular thickness, but careful interpretation by a clinician is needed.