Abstract
We introduce streptavidin-functionalized (SAF) hydrogel microparticles for highly flexible biomolecule detection. Immobilized streptavidin in hydrogel microparticles enable the rapid probe-set modification by virtue of streptavidin-biotin interaction with biotinylated probes, which provide highly customizable multiplex biomolecule detection. We demonstrate the high assay capability of SAF hydrogel microparticles by performing multiplex detection of two DNA targets.
| Original language | English |
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| Title of host publication | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1122-1123 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781733419000 |
| Publication status | Published - 2019 |
| Event | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland Duration: 2019 Oct 27 → 2019 Oct 31 |
Publication series
| Name | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
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Conference
| Conference | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
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| Country/Territory | Switzerland |
| City | Basel |
| Period | 19/10/27 → 19/10/31 |
Bibliographical note
Publisher Copyright:© 2019 CBMS-0001.
Keywords
- Aza-Michael Addition
- Hydrogel Microparticle
- Multiplex Assay
- Streptavidin
ASJC Scopus subject areas
- Bioengineering
- Chemical Engineering (miscellaneous)