Structural Study on the Impact of S239D/I332E Mutations in the Binding of Fc and FcγRIIIa

Keyphrases

• Salt Bridge 100%
• Point mutation 66%
• Combined mutation 66%
• Fc Variants 66%
• Monoclonal Antibody 33%
• Design Basis 33%
• Structural Insights 33%
• Molecular Interactions 33%
• Therapeutic Action 33%
• Specific Point 33%
• Mutation Study 33%
• Beta Chain 33%
• Homodimeric 33%
• Structural Effect 33%
• Fc Domain 33%
• Engineering Studies 33%
• Docking Technique 33%
• Salt Bridge Formation 33%
• Fc Engineering 33%
• Computational Docking 33%
• Variant Design 33%
• Complex Salt 33%

Biochemistry, Genetics and Molecular Biology

• Point Mutation 100%
• Monoclonal Antibody 100%
• Molecular Interaction 100%