Studies of the diastereoselective alkylation of enolate dianion of (S)-4-carboethoxymethyl-2-oxazolidinone

Deok Chan Ha; Kun Eek Kil; Kwang Sun Choi; Hye Sang Park

doi:10.1016/0040-4039(96)01210-5

Studies of the diastereoselective alkylation of enolate dianion of (S)-4-carboethoxymethyl-2-oxazolidinone

Deok Chan Ha, Kun Eek Kil, Kwang Sun Choi, Hye Sang Park

College of Science

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Diastereoselective alkylation of enolate dianion of (S)-4-carboethyoxymethyl-2-oxazolidinone has been studied. The increased anti-selectivity in the presence of HMPA was explained by stereoelectronic effect of the electron-rich nitrogen atom of the oxazolidinone amidate.

Original language	English
Pages (from-to)	5723-5726
Number of pages	4
Journal	Tetrahedron Letters
Volume	37
Issue number	32
DOIs	https://doi.org/10.1016/0040-4039(96)01210-5
Publication status	Published - 1996 Aug 5

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(96)01210-5

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abstract = "Diastereoselective alkylation of enolate dianion of (S)-4-carboethyoxymethyl-2-oxazolidinone has been studied. The increased anti-selectivity in the presence of HMPA was explained by stereoelectronic effect of the electron-rich nitrogen atom of the oxazolidinone amidate.",

author = "Ha, {Deok Chan} and Kil, {Kun Eek} and Choi, {Kwang Sun} and Park, {Hye Sang}",

note = "Funding Information: Acknowledgment. Financial support from Korea Science and Engineering Foundation, and Ministry of Education through Basic Research Institute Program is gratefully acknowledged.",

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AU - Ha, Deok Chan

AU - Kil, Kun Eek

AU - Choi, Kwang Sun

AU - Park, Hye Sang

N1 - Funding Information: Acknowledgment. Financial support from Korea Science and Engineering Foundation, and Ministry of Education through Basic Research Institute Program is gratefully acknowledged.

PY - 1996/8/5

Y1 - 1996/8/5

N2 - Diastereoselective alkylation of enolate dianion of (S)-4-carboethyoxymethyl-2-oxazolidinone has been studied. The increased anti-selectivity in the presence of HMPA was explained by stereoelectronic effect of the electron-rich nitrogen atom of the oxazolidinone amidate.

AB - Diastereoselective alkylation of enolate dianion of (S)-4-carboethyoxymethyl-2-oxazolidinone has been studied. The increased anti-selectivity in the presence of HMPA was explained by stereoelectronic effect of the electron-rich nitrogen atom of the oxazolidinone amidate.

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ER -

Studies of the diastereoselective alkylation of enolate dianion of (S)-4-carboethoxymethyl-2-oxazolidinone

Abstract

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