Abstract
Diastereoselective alkylation of enolate dianion of (S)-4-carboethyoxymethyl-2-oxazolidinone has been studied. The increased anti-selectivity in the presence of HMPA was explained by stereoelectronic effect of the electron-rich nitrogen atom of the oxazolidinone amidate.
Original language | English |
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Pages (from-to) | 5723-5726 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 37 |
Issue number | 32 |
DOIs | |
Publication status | Published - 1996 Aug 5 |
Bibliographical note
Funding Information:Acknowledgment. Financial support from Korea Science and Engineering Foundation, and Ministry of Education through Basic Research Institute Program is gratefully acknowledged.
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry