Studies of the diastereoselective alkylation of enolate dianion of (S)-4-carboethoxymethyl-2-oxazolidinone

Deok Chan Ha; Kun Eek Kil; Kwang Sun Choi; Hye Sang Park

doi:10.1016/0040-4039(96)01210-5

Studies of the diastereoselective alkylation of enolate dianion of (S)-4-carboethoxymethyl-2-oxazolidinone

Deok Chan Ha^*, Kun Eek Kil, Kwang Sun Choi, Hye Sang Park

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Diastereoselective alkylation of enolate dianion of (S)-4-carboethyoxymethyl-2-oxazolidinone has been studied. The increased anti-selectivity in the presence of HMPA was explained by stereoelectronic effect of the electron-rich nitrogen atom of the oxazolidinone amidate.

Original language	English
Pages (from-to)	5723-5726
Number of pages	4
Journal	Tetrahedron Letters
Volume	37
Issue number	32
DOIs	https://doi.org/10.1016/0040-4039(96)01210-5
Publication status	Published - 1996 Aug 5

Bibliographical note

Funding Information:
Acknowledgment. Financial support from Korea Science and Engineering Foundation, and Ministry of Education through Basic Research Institute Program is gratefully acknowledged.

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/0040-4039(96)01210-5

Cite this

@article{ddf13fcbde264dd6b2b20c55a7b32b6a,

title = "Studies of the diastereoselective alkylation of enolate dianion of (S)-4-carboethoxymethyl-2-oxazolidinone",

abstract = "Diastereoselective alkylation of enolate dianion of (S)-4-carboethyoxymethyl-2-oxazolidinone has been studied. The increased anti-selectivity in the presence of HMPA was explained by stereoelectronic effect of the electron-rich nitrogen atom of the oxazolidinone amidate.",

author = "Ha, \{Deok Chan\} and Kil, \{Kun Eek\} and Choi, \{Kwang Sun\} and Park, \{Hye Sang\}",

note = "Funding Information: Acknowledgment. Financial support from Korea Science and Engineering Foundation, and Ministry of Education through Basic Research Institute Program is gratefully acknowledged.",

year = "1996",

month = aug,

day = "5",

doi = "10.1016/0040-4039(96)01210-5",

language = "English",

volume = "37",

pages = "5723--5726",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "32",

}

TY - JOUR

T1 - Studies of the diastereoselective alkylation of enolate dianion of (S)-4-carboethoxymethyl-2-oxazolidinone

AU - Ha, Deok Chan

AU - Kil, Kun Eek

AU - Choi, Kwang Sun

AU - Park, Hye Sang

N1 - Funding Information: Acknowledgment. Financial support from Korea Science and Engineering Foundation, and Ministry of Education through Basic Research Institute Program is gratefully acknowledged.

PY - 1996/8/5

Y1 - 1996/8/5

N2 - Diastereoselective alkylation of enolate dianion of (S)-4-carboethyoxymethyl-2-oxazolidinone has been studied. The increased anti-selectivity in the presence of HMPA was explained by stereoelectronic effect of the electron-rich nitrogen atom of the oxazolidinone amidate.

AB - Diastereoselective alkylation of enolate dianion of (S)-4-carboethyoxymethyl-2-oxazolidinone has been studied. The increased anti-selectivity in the presence of HMPA was explained by stereoelectronic effect of the electron-rich nitrogen atom of the oxazolidinone amidate.

UR - https://www.scopus.com/pages/publications/0030570903

U2 - 10.1016/0040-4039(96)01210-5

DO - 10.1016/0040-4039(96)01210-5

M3 - Article

AN - SCOPUS:0030570903

SN - 0040-4039

VL - 37

SP - 5723

EP - 5726

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 32

ER -

Studies of the diastereoselective alkylation of enolate dianion of (S)-4-carboethoxymethyl-2-oxazolidinone

Abstract

Bibliographical note

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this