Supramolecular Two-Dimensional Systems and Their Biological Applications

Taeyeon Kim, Jung Yeon Park, Jiwon Hwang, Gunhee Seo, Yongju Kim

    Research output: Contribution to journalArticlepeer-review

    34 Citations (Scopus)

    Abstract

    Various biological systems rely on the supramolecular assembly of biomolecules through noncovalent bonds for performing sophisticated functions. In particular, cell membranes, which are 2D structures in biological systems, have various characteristics such as a large surface, flexibility, and molecule-recognition ability. Supramolecular 2D materials based on biological systems provide a novel perspective for the development of functional 2D materials. The physical and chemical properties of 2D structures, attributed to their large surface area, can enhance the sensitivity of the detection of target molecules, molecular loading, and bioconjugation efficiency, suggesting the potential utility of functional 2D materials as candidates for biological systems. Although several types of studies on supramolecular 2D materials have been reported, supramolecular biofunctional 2D materials have not been reviewed previously. In this regard, the current advances in 2D material development using molecular assembly are discussed with respect to the rational design of self-assembling aromatic amphiphiles, the formation of 2D structures, and the biological applications of functional 2D materials.

    Original languageEnglish
    Article number2002405
    JournalAdvanced Materials
    Volume32
    Issue number51
    DOIs
    Publication statusPublished - 2020 Dec 22

    Bibliographical note

    Funding Information:
    T.K. and J.Y.P. contributed equally to this work. This work was supported by the National Research Foundation of Korea (NRF‐2019R1C1C1008526 and NRF‐2019R1A4A1027627), a Korea University grant, and the KU‐KIST School Project.

    Funding Information:
    T.K. and J.Y.P. contributed equally to this work. This work was supported by the National Research Foundation of Korea (NRF-2019R1C1C1008526 and NRF-2019R1A4A1027627), a Korea University grant, and the KU-KIST School Project.

    Publisher Copyright:
    © 2020 Wiley-VCH GmbH

    Keywords

    • 2D materials
    • aromatic amphiphiles
    • biological functions
    • lateral interactions
    • supramolecules

    ASJC Scopus subject areas

    • General Materials Science
    • Mechanics of Materials
    • Mechanical Engineering

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