TY - JOUR
T1 - Supramolecular Two-Dimensional Systems and Their Biological Applications
AU - Kim, Taeyeon
AU - Park, Jung Yeon
AU - Hwang, Jiwon
AU - Seo, Gunhee
AU - Kim, Yongju
N1 - Funding Information:
T.K. and J.Y.P. contributed equally to this work. This work was supported by the National Research Foundation of Korea (NRF‐2019R1C1C1008526 and NRF‐2019R1A4A1027627), a Korea University grant, and the KU‐KIST School Project.
Funding Information:
T.K. and J.Y.P. contributed equally to this work. This work was supported by the National Research Foundation of Korea (NRF-2019R1C1C1008526 and NRF-2019R1A4A1027627), a Korea University grant, and the KU-KIST School Project.
Publisher Copyright:
© 2020 Wiley-VCH GmbH
PY - 2020/12/22
Y1 - 2020/12/22
N2 - Various biological systems rely on the supramolecular assembly of biomolecules through noncovalent bonds for performing sophisticated functions. In particular, cell membranes, which are 2D structures in biological systems, have various characteristics such as a large surface, flexibility, and molecule-recognition ability. Supramolecular 2D materials based on biological systems provide a novel perspective for the development of functional 2D materials. The physical and chemical properties of 2D structures, attributed to their large surface area, can enhance the sensitivity of the detection of target molecules, molecular loading, and bioconjugation efficiency, suggesting the potential utility of functional 2D materials as candidates for biological systems. Although several types of studies on supramolecular 2D materials have been reported, supramolecular biofunctional 2D materials have not been reviewed previously. In this regard, the current advances in 2D material development using molecular assembly are discussed with respect to the rational design of self-assembling aromatic amphiphiles, the formation of 2D structures, and the biological applications of functional 2D materials.
AB - Various biological systems rely on the supramolecular assembly of biomolecules through noncovalent bonds for performing sophisticated functions. In particular, cell membranes, which are 2D structures in biological systems, have various characteristics such as a large surface, flexibility, and molecule-recognition ability. Supramolecular 2D materials based on biological systems provide a novel perspective for the development of functional 2D materials. The physical and chemical properties of 2D structures, attributed to their large surface area, can enhance the sensitivity of the detection of target molecules, molecular loading, and bioconjugation efficiency, suggesting the potential utility of functional 2D materials as candidates for biological systems. Although several types of studies on supramolecular 2D materials have been reported, supramolecular biofunctional 2D materials have not been reviewed previously. In this regard, the current advances in 2D material development using molecular assembly are discussed with respect to the rational design of self-assembling aromatic amphiphiles, the formation of 2D structures, and the biological applications of functional 2D materials.
KW - 2D materials
KW - aromatic amphiphiles
KW - biological functions
KW - lateral interactions
KW - supramolecules
UR - http://www.scopus.com/inward/record.url?scp=85091682148&partnerID=8YFLogxK
U2 - 10.1002/adma.202002405
DO - 10.1002/adma.202002405
M3 - Article
C2 - 32989841
AN - SCOPUS:85091682148
SN - 0935-9648
VL - 32
JO - Advanced Materials
JF - Advanced Materials
IS - 51
M1 - 2002405
ER -