Abstract
In the present study, we investigated the surface reorganization behaviors and adsorption conformations of fibrinogen on the surface of polyrotaxanes containing different amounts of α-cyclodextrin (α-CD) by using surface-sensitive vibrational spectroscopy sum frequency generation (SFG). For comparison, behaviors of the surface restructuring and fibrinogen adsorption on the random copolymers containing similar terminal groups were also investigated. It was found that larger amounts of BMA moieties of polyrotaxanes form ordered surface structures after immersion in water for 48 h. Furthermore, the polyrotaxane surfaces exhibit a much higher capability of fibrinogen adsorption than the random copolymer surfaces. The water-induced surface restructuring of the polyrotaxane films slightly affects the adsorption structure of the fibrinogen molecules.
Original language | English |
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Pages (from-to) | 12463-12470 |
Number of pages | 8 |
Journal | Langmuir |
Volume | 34 |
Issue number | 41 |
DOIs | |
Publication status | Published - 2018 Oct 16 |
Bibliographical note
Funding Information:This research is partly supported by a Grant-in-Aid for Scientific Research (B) 17H01879 from the Ministry of Education, Culture, Sports, Science & Technology (MEXT), Japan. N.Y. acknowledges a Grant-in-Aid for Scientific Research (A) 16H01852 from MEXT, Japan.
Publisher Copyright:
© 2018 American Chemical Society.
ASJC Scopus subject areas
- General Materials Science
- Condensed Matter Physics
- Surfaces and Interfaces
- Spectroscopy
- Electrochemistry