Sustainable and Highly Reactive Nerve-Agent Simulant Detoxification: Effective Amine Buffers for Metal-Organic Framework Catalysts

Jin Young Seo, Jung Hyun Lee, Kie Yong Cho, Keunhong Jeong, Kyung Youl Baek

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


The appropriate treatment of chemical warfare agents (CWAs) is essential because of their toxicity and lethality. Metal-organic framework (MOF) catalysts, with the assistance of a volatile small molecule buffer, have been reported to be effective for the destruction of CWAs. However, employing small molecular volatile buffers not only contaminates the catalysts and causes them to lose their activity but also prevents their practical application. In this study, we report a novel polymeric buffer that can enhance the catalytic ability of MOFs without contamination of the catalyst. The macromolecular chain can provide non-flowability to buffer, as well as inhibit catalyst contamination by steric hindrance while maintaining activity as a buffer. The optimized polymer buffer [P(MEMA)43] can effectively degrade nerve-agent simulants (7.7 min of t1/2) in the presence of UiO-66 and preserve its catalytic activity by more than 90% even after three cycles. In addition, the polymeric composite with MOFs coated on a cotton substrate shows excellent detoxification performance in humidified conditions (RH 99%). This fundamental study on a sustainable CWA destruction catalytic system is anticipated to be promising for developing chemical protective textiles against CWAs.

Original languageEnglish
Pages (from-to)1624-1632
Number of pages9
JournalChemistry of Materials
Issue number4
Publication statusPublished - 2023 Feb 28

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF-2020M3H4A3106403) and partially supported by the Korea Institute of Science and Technology (KIST) through the KIST Institutional program (2E31761).

Publisher Copyright:
© 2023 American Chemical Society.

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering
  • Materials Chemistry


Dive into the research topics of 'Sustainable and Highly Reactive Nerve-Agent Simulant Detoxification: Effective Amine Buffers for Metal-Organic Framework Catalysts'. Together they form a unique fingerprint.

Cite this