Synthesis and structure - Activity relationships of quarternary ammonium cephalosporins with 3-pyrazolylpyridium derivatives

Kwan Young Chang; Sung Hoon Kim; Ghilsoo Nam; Jae Hong Seo; Joong Hyup Kim; Deok Chan Ha

doi:10.1016/S0960-894X(00)00203-1

Synthesis and structure - Activity relationships of quarternary ammonium cephalosporins with 3-pyrazolylpyridium derivatives

Kwan Young Chang, Sung Hoon Kim, Ghilsoo Nam, Jae Hong Seo, Joong Hyup Kim, Deok Chan Ha

College of Science

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Cephalosporins with 3-pyazolylpyridinium at C-3 position, which is supposed to exhibit synergic activity of ceftazidime and cefoselis, were synthesized and their antibacterial activity against Gram-positive and Gram-negative was inspected. (C) 2000 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	1211-1214
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	10
Issue number	11
DOIs	https://doi.org/10.1016/S0960-894X(00)00203-1
Publication status	Published - 2000 Jun 5

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/S0960-894X(00)00203-1

Cite this

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title = "Synthesis and structure - Activity relationships of quarternary ammonium cephalosporins with 3-pyrazolylpyridium derivatives",

abstract = "Cephalosporins with 3-pyazolylpyridinium at C-3 position, which is supposed to exhibit synergic activity of ceftazidime and cefoselis, were synthesized and their antibacterial activity against Gram-positive and Gram-negative was inspected. (C) 2000 Elsevier Science Ltd. All rights reserved.",

author = "Chang, {Kwan Young} and Kim, {Sung Hoon} and Ghilsoo Nam and Seo, {Jae Hong} and Kim, {Joong Hyup} and Ha, {Deok Chan}",

note = "Funding Information: This work was financially supported by MOST (2N20090). MIC values were checked by Dr. Eun Rhan Woo and Sun Hee Suh. We greatly appreciate their efforts.",

year = "2000",

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doi = "10.1016/S0960-894X(00)00203-1",

language = "English",

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T1 - Synthesis and structure - Activity relationships of quarternary ammonium cephalosporins with 3-pyrazolylpyridium derivatives

AU - Chang, Kwan Young

AU - Kim, Sung Hoon

AU - Nam, Ghilsoo

AU - Seo, Jae Hong

AU - Kim, Joong Hyup

AU - Ha, Deok Chan

N1 - Funding Information: This work was financially supported by MOST (2N20090). MIC values were checked by Dr. Eun Rhan Woo and Sun Hee Suh. We greatly appreciate their efforts.

PY - 2000/6/5

Y1 - 2000/6/5

N2 - Cephalosporins with 3-pyazolylpyridinium at C-3 position, which is supposed to exhibit synergic activity of ceftazidime and cefoselis, were synthesized and their antibacterial activity against Gram-positive and Gram-negative was inspected. (C) 2000 Elsevier Science Ltd. All rights reserved.

AB - Cephalosporins with 3-pyazolylpyridinium at C-3 position, which is supposed to exhibit synergic activity of ceftazidime and cefoselis, were synthesized and their antibacterial activity against Gram-positive and Gram-negative was inspected. (C) 2000 Elsevier Science Ltd. All rights reserved.

UR - http://www.scopus.com/inward/record.url?scp=0034608562&partnerID=8YFLogxK

U2 - 10.1016/S0960-894X(00)00203-1

DO - 10.1016/S0960-894X(00)00203-1

M3 - Article

C2 - 10866383

AN - SCOPUS:0034608562

SN - 0960-894X

VL - 10

SP - 1211

EP - 1214

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 11

ER -

Synthesis and structure - Activity relationships of quarternary ammonium cephalosporins with 3-pyrazolylpyridium derivatives

Abstract

ASJC Scopus subject areas

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