Abstract
Flow on: Flow microreactors enable the generation of aryl lithium compounds and subsequent electrophilic fluorination with NFSI and N-fluorosultam. The reaction can be successfully accomplished to synthesize various aryl fluorides involving an electron-withdrawing, an electron-donating, and a sterically hindered functional group in good yields.
Original language | English |
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Pages (from-to) | 705-708 |
Number of pages | 4 |
Journal | Chemistry - An Asian Journal |
Volume | 8 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2013 Apr |
Externally published | Yes |
Keywords
- fluorination
- lithiation
- microreactors
- synthetic methods
ASJC Scopus subject areas
- General Chemistry
- Biochemistry
- Organic Chemistry