Enantiomerically pure 3-substituted-5-amino-4-hydroxy-5,6-dihydro-4H- pyrrolo[1,2-c][1,2,3]triazoles were synthesized efficiently from the sequential reactions including a regioselective ring-opening of 1-aziridine-2-y1- propargylic alcohols by azidotrimethylsilane and the subsequent intramolecular 1,3-dipolar cycloaddition between alkyne and azide.
|Number of pages||4|
|Publication status||Published - 2005 Sept 2|
ASJC Scopus subject areas
- Organic Chemistry