Abstract
Enantiomerically pure 3-substituted-5-amino-4-hydroxy-5,6-dihydro-4H- pyrrolo[1,2-c][1,2,3]triazoles were synthesized efficiently from the sequential reactions including a regioselective ring-opening of 1-aziridine-2-y1- propargylic alcohols by azidotrimethylsilane and the subsequent intramolecular 1,3-dipolar cycloaddition between alkyne and azide.
Original language | English |
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Pages (from-to) | 2187-2190 |
Number of pages | 4 |
Journal | Synlett |
Issue number | 14 |
DOIs | |
Publication status | Published - 2005 Sept 2 |
Externally published | Yes |
Keywords
- Alkyne
- Azide
- Aziridine
- Cycloaddition
- Triazole
ASJC Scopus subject areas
- Organic Chemistry