Abstract
Aryl iodides and aryl sulfonyl hydrazides were reacted with carbon monoxide in the presence of DBU and a palladium catalyst to provide optimal yields of S-aryl thioesters. Aryl sulfonyl hydrazides served as aryl thiol surrogates. Optimal results were obtained when the reaction was carried out with Pd(dba)2/dppb in toluene at 80 °C for 12 h. The methodology exhibits superior functional group tolerance, being compatible with moieties like fluoride, chloride, bromide, ester, ketone, cyanide and nitro.
Original language | English |
---|---|
Pages (from-to) | 2938-2943 |
Number of pages | 6 |
Journal | Organic Chemistry Frontiers |
Volume | 7 |
Issue number | 19 |
DOIs | |
Publication status | Published - 2020 Oct 7 |
Bibliographical note
Publisher Copyright:© 2020 the Partner Organisations.
ASJC Scopus subject areas
- Organic Chemistry