Symmetric diarylalkynes were obtained from the decarboxylative coupling reactions of aryl bromides and propiolic acid in water solvent condition. In the presence of phase transfer surfactant C18H37N(CH 3)3Cl, the catalytic system of both Pd(PPh 3)2Cl2/dppb and Pd(TPPMS)2Cl 2/TPPMS afforded the desired coupled products in good yields.
Bibliographical noteFunding Information:
This work was supported by the Korea Research Foundation Grant funded by the Korean Government ( MOEHRD , Basic Research Promotion Fund) (KRF-2008-314-D00070).
- Decarboxylative coupling
- Propiolic acid
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry