Targeted nanotheranostics for future personalized medicine: Recent progress in cancer therapy

Sung Duk Jo; Sook Hee Ku; You Yeon Won; Sun Hwa Kim; Ick Chan Kwon

doi:10.7150/thno.15335

Targeted nanotheranostics for future personalized medicine: Recent progress in cancer therapy

Sung Duk Jo, Sook Hee Ku, You Yeon Won, Sun Hwa Kim, Ick Chan Kwon

KU-KIST Graduate School of Converging Science and Technology

Research output: Contribution to journal › Review article › peer-review

155 Citations (Scopus)

Abstract

Recently, many theranostic nanomaterials have been developed by integrating therapeutic and diagnostic agents in a single regimen. Real-time visualization of nano drug carrier biodistributions, drug release processes and therapeutic responses can provide critical information needed for dynamically optimizing treatment operations in a personalized manner in real time. This review highlights recent progresses in the development of multifunctional nanoparticles possessing both therapeutic and imaging functionalities for cancer therapy. The advantages of using nanoparticle platforms are discussed. Examples demonstrating various combinations of imaging and therapeutic modalities are highlighted.

Original language	English
Pages (from-to)	1362-1377
Number of pages	16
Journal	Theranostics
Volume	6
Issue number	9
DOIs	https://doi.org/10.7150/thno.15335
Publication status	Published - 2016

Keywords

Cancer therapy
Nanotheranostics
Personalized medicine

ASJC Scopus subject areas

Medicine (miscellaneous)
Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.7150/thno.15335

Cite this

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title = "Targeted nanotheranostics for future personalized medicine: Recent progress in cancer therapy",

abstract = "Recently, many theranostic nanomaterials have been developed by integrating therapeutic and diagnostic agents in a single regimen. Real-time visualization of nano drug carrier biodistributions, drug release processes and therapeutic responses can provide critical information needed for dynamically optimizing treatment operations in a personalized manner in real time. This review highlights recent progresses in the development of multifunctional nanoparticles possessing both therapeutic and imaging functionalities for cancer therapy. The advantages of using nanoparticle platforms are discussed. Examples demonstrating various combinations of imaging and therapeutic modalities are highlighted.",

keywords = "Cancer therapy, Nanotheranostics, Personalized medicine",

author = "Jo, {Sung Duk} and Ku, {Sook Hee} and Won, {You Yeon} and Kim, {Sun Hwa} and Kwon, {Ick Chan}",

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T2 - Recent progress in cancer therapy

AU - Jo, Sung Duk

AU - Ku, Sook Hee

AU - Won, You Yeon

AU - Kim, Sun Hwa

AU - Kwon, Ick Chan

N1 - Publisher Copyright: © Ivyspring International Publisher.

PY - 2016

Y1 - 2016

N2 - Recently, many theranostic nanomaterials have been developed by integrating therapeutic and diagnostic agents in a single regimen. Real-time visualization of nano drug carrier biodistributions, drug release processes and therapeutic responses can provide critical information needed for dynamically optimizing treatment operations in a personalized manner in real time. This review highlights recent progresses in the development of multifunctional nanoparticles possessing both therapeutic and imaging functionalities for cancer therapy. The advantages of using nanoparticle platforms are discussed. Examples demonstrating various combinations of imaging and therapeutic modalities are highlighted.

AB - Recently, many theranostic nanomaterials have been developed by integrating therapeutic and diagnostic agents in a single regimen. Real-time visualization of nano drug carrier biodistributions, drug release processes and therapeutic responses can provide critical information needed for dynamically optimizing treatment operations in a personalized manner in real time. This review highlights recent progresses in the development of multifunctional nanoparticles possessing both therapeutic and imaging functionalities for cancer therapy. The advantages of using nanoparticle platforms are discussed. Examples demonstrating various combinations of imaging and therapeutic modalities are highlighted.

KW - Cancer therapy

KW - Nanotheranostics

KW - Personalized medicine

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U2 - 10.7150/thno.15335

DO - 10.7150/thno.15335

M3 - Review article

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AN - SCOPUS:84991615377

SN - 1838-7640

VL - 6

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EP - 1377

JO - Theranostics

JF - Theranostics

IS - 9

ER -

Targeted nanotheranostics for future personalized medicine: Recent progress in cancer therapy

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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