Ten-year nationwide population-based survey on the characteristics of children with Henoch-Schönlein Purpura in Korea

Jung Ok Shim, Kyoungdo Han, Sanghyun Park, Gun Ha Kim, Jae Sung Ko, Ju Young Chung

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    25 Citations (Scopus)


    Background: Henoch-Schönlein purpura (HSP) is a common vasculitis of childhood. Though HSP is usually self-limiting, severe complications can occur. The management for this condition has not been established yet. Thus, this nationwide study aimed at investigating epidemiological characteristics of children with HSP in Korea. The patterns of clinical practice with regard to the complications of the condition were also investigated. Methods: This is a national population-based study that used the National Health Insurance Database. Children below 18 years who were diagnosed with HSP in Korea between 2006 and 2015 were enrolled. Data, such as age, sex, yearly and monthly distribution of HSP, hospitalization, re-hospitalization, comorbidities, and interventions were obtained. The use of steroids was also analyzed. Results: A total of 56,841 children were enrolled. The annual incidence of HSP was 55.9 per 100,000 children. The peak age was 5 years. Spring was the most prevalent season. Sex (male) and young age ( < 9 years) were risk factors of hospitalization. Younger children were more likely to be re-hospitalized and suspected with intussusception, arthritis, and nephritis. Only 4 children received laparotomy. In total, 57% were managed with steroids, and mean durations of medication were 4-5 days. Children who were hospitalized and those with comorbidities used steroids more frequently (P < 0.001). Conclusion: The annual incidence of HSP is 55.9 per 100,000 children which is higher in Korea than that in other countries. Younger children can have a more severe clinical course. This nationwide survey provides valuable information to understand HSP in children and to inspire further research on HSP.

    Original languageEnglish
    Article numbere174
    JournalJournal of Korean medical science
    Issue number25
    Publication statusPublished - 2018 Jun 1

    Bibliographical note

    Publisher Copyright:
    © 2018 The Korean Academy of Medical Sciences.


    • Child
    • Epidemiology
    • Henoch-Schönlein Purpura
    • Korea
    • Steroids

    ASJC Scopus subject areas

    • General Medicine


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