Tetra-PEG based cell-cartons: Tetra-PEG micro-chamber arrays for cell spheroid formation

H. E. Jeong, Y. J. Heo, Seok Chung, A. Sakuma

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Cell implantation has been garnering attention for the treatment of diverse diseases, including diabetes and cancers. Hydrogel-based scaffolds have been employed for obtaining biocompatible microenvironment and immunoisolation. Many types of cell implantation carriers were presented, but they have yet to be realized ideal cellular environment mainly due to has yet cell leakage problems from unwanted degradation and the low cell viabilities. Here, we develop a cell carton based on mechanically-strong hydrogel, tetra-polyethylene glycol (PEG), and characterize tetra-PEG material properties and potential for cell carriers. We envision that the present cell-spheroids carrier can be a cell implantation platform for cell therapy with less cell-loss and high cell-viability.

    Original languageEnglish
    Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
    PublisherChemical and Biological Microsystems Society
    Pages582-584
    Number of pages3
    ISBN (Electronic)9780979806483
    Publication statusPublished - 2015
    Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
    Duration: 2015 Oct 252015 Oct 29

    Other

    Other19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
    Country/TerritoryKorea, Republic of
    CityGyeongju
    Period15/10/2515/10/29

    Keywords

    • 3D culture
    • Cell spheroid
    • Cell therapy
    • Tetra-PEG

    ASJC Scopus subject areas

    • Control and Systems Engineering

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