The effect of the response to the coronavirus disease pandemic on treatment outcomes in patients with lymphoma and multiple myeloma

Ka Won Kang, Byung Hyun Lee, Min Ji Jeon, Eun Sang Yu, Dae Sik Kim, Se Ryeon Lee, Hwa Jung Sung, Chul Won Choi, Yong Park, Byung Soo Kim

Research output: Contribution to journalArticlepeer-review

Abstract

Background/Aims: Relatively little data are available on how the response to the coronavirus disease 2019 (COVID-19) pandemic has affected treatment outcomes in patients receiving chemotherapy for lymphoma or multiple myeloma. We aimed to determine the effect of COVID-19 countermeasures on treatment outcomes in this patient population. Methods: We retrospectively analyzed data on patients treated for lymphoma or multiple myeloma in two tertiary hospitals in Seoul. Patients were divided into two groups: group 1 included patients who received chemotherapy between September and December 2019 (the control period), and group 2 included patients who received chemotherapy between September and December 2020 (the study period). Countermeasures to COVID-19 were applied to the patients in group 2. The countermeasures implemented included mask wearing and regular hand-washing at home and in hospital; COVID-19 risk assessments on all hospital visitors; and pre-emptive COVID-19 screening for all newly hospitalized patients and their resident guardians. Results: No differences in treatment outcomes, including treatment response, incidence and duration of neutropenia or neutropenic fever, delays in chemo-therapy, or number of deaths during chemotherapy, were observed between the g roups. None of the patients in group 2 tested positive for COVID-19, and there were no COVID-19-related deaths during the study period. Conclusions: Countermeasures to COVID-19 did not affect treatment outcomes in patients receiving chemotherapy for lymphoma or multiple myeloma. Data on the effect of countermeasures to COVID-19 on treatment outcomes should continue to be analyzed to ensure that treatment outcomes are not adversely affected.

Original languageEnglish
Pages (from-to)1459-1470
Number of pages12
JournalKorean Journal of Internal Medicine
Volume36
Issue number6
DOIs
Publication statusPublished - 2021 Nov

Bibliographical note

Funding Information:
This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) and Korea Infectious Diseases Clinical Trials Initiative, funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HE21C0001).

Publisher Copyright:
© 2021 The Korean Association of Internal Medicine.

Keywords

  • Coronavirus
  • Lymphoma
  • Multiple myeloma
  • Treatment outcome

ASJC Scopus subject areas

  • Internal Medicine

Fingerprint

Dive into the research topics of 'The effect of the response to the coronavirus disease pandemic on treatment outcomes in patients with lymphoma and multiple myeloma'. Together they form a unique fingerprint.

Cite this