A facile one-step transformation of methylsulfanyl and arylsulfanyl groups on pyrimidine ring system into the corresponding chloride group was achieved using sulfuryl chloride in acetonitrile/dichloromethane.
Bibliographical noteFunding Information:
This work was supported by KOSFFL (The Korea Scholarship Foundation for the Future Leaders) program.
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry