The relationship between morphology and function of the meibomian glands

Hyo Myung Kim, Youngsub Eom, Jong Suk Song

    Research output: Contribution to journalReview articlepeer-review

    47 Citations (Scopus)


    Meibomian gland dysfunction (MGD) is a leading cause of dry eye disease (DED). Meibomian gland dysfunction is divided into two major categories based on meibomian gland secretion: low delivery and high delivery. The low-delivery states are further classified as either hyposecretory or obstructive subtype, and the high-delivery state is termed “hypersecretory MGD.” Two parameters are commonly used to evaluate meibomian gland function: lipid layer thickness and meibum quality and expressibility. To evaluate the morphology of meibomian glands, meibography is used to detect meibomian gland dropout. Functional and morphological changes of meibomian glands are often thought to be well correlated; in reality, many cases do not because some patients have characteristics of both hypersecretory and obstructive subtypes. We suggest that the MGD classification system should be modified to include a mixed subtype to explain such patients.

    Original languageEnglish
    Pages (from-to)1-5
    Number of pages5
    JournalEye and Contact Lens
    Issue number1
    Publication statusPublished - 2018

    Bibliographical note

    Funding Information:
    From the Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea. The authors have no funding or conflicts of interest to disclose. Supported by the Korean Health Technology R&D Project, Ministry for Health, Welfare & Family Affairs, Republic of Korea (HI13C0055). Presented at the fourth Lid and Meibomian Gland International Meeting in May 4, 2016, Seattle, WA. Address correspondence to Jong Suk Song, M.D., Ph.D., Department of Ophthalmology, Guro Hospital, Korea University College of Medicine, 80, Guro-dong, Guro-gu, Seoul 152–703, South Korea; e-mail: crisim@ Accepted August 28, 2016.

    Publisher Copyright:
    © 2016 Contact Lens Association of Ophthalmologists


    • Classification
    • Meibography
    • Meibomian gland dysfunction

    ASJC Scopus subject areas

    • Ophthalmology


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