The role of dynamic changes in blood perfusion and optical properties in thermal coagulation of the prostate

Beop Min Kim; Steven L. Jacques; Sohi Rastegar; Sharon Thomsen; Massoud Motamedi

doi:10.1117/12.209911

The role of dynamic changes in blood perfusion and optical properties in thermal coagulation of the prostate

Beop Min Kim, Steven L. Jacques, Sohi Rastegar, Sharon Thomsen, Massoud Motamedi

Research output: Contribution to journal › Conference article › peer-review

17 Citations (Scopus)

Abstract

The dynamic evolution of the coagulation front in laser irradiated prostate tissue is simulated using a nonlinear finite element method (NFEM) which takes into account the temperature and thermal damage dependence of blood perfusion rate and optical properties. Using this nonlinear model, it wasfound that the hyperemic ringformed at the periphery of the coagulationfront reduces heatpenetration significantly and the increased scattering near the tissue surface reduces the light energy deposition in the deep region. Thefinal damage depth would be overestimated by about 50% ifthe effect oftemperature and damage dependence of blood perfusion and opticalproperties modeling is disregarded.

Original language	English
Pages (from-to)	443-450
Number of pages	8
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	2391
DOIs	https://doi.org/10.1117/12.209911
Publication status	Published - 1995 May 22
Externally published	Yes
Event	Laser-Tissue Interaction VI 1995 - San Jose, United States Duration: 1995 Feb 1 → 1995 Feb 8

Bibliographical note

Publisher Copyright:
© 1995 SPIE. All rights reserved.

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.209911

Cite this

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title = "The role of dynamic changes in blood perfusion and optical properties in thermal coagulation of the prostate",

abstract = "The dynamic evolution of the coagulation front in laser irradiated prostate tissue is simulated using a nonlinear finite element method (NFEM) which takes into account the temperature and thermal damage dependence of blood perfusion rate and optical properties. Using this nonlinear model, it wasfound that the hyperemic ringformed at the periphery of the coagulationfront reduces heatpenetration significantly and the increased scattering near the tissue surface reduces the light energy deposition in the deep region. Thefinal damage depth would be overestimated by about 50% ifthe effect oftemperature and damage dependence of blood perfusion and opticalproperties modeling is disregarded.",

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T1 - The role of dynamic changes in blood perfusion and optical properties in thermal coagulation of the prostate

AU - Kim, Beop Min

AU - Jacques, Steven L.

AU - Rastegar, Sohi

AU - Thomsen, Sharon

AU - Motamedi, Massoud

PY - 1995/5/22

Y1 - 1995/5/22

N2 - The dynamic evolution of the coagulation front in laser irradiated prostate tissue is simulated using a nonlinear finite element method (NFEM) which takes into account the temperature and thermal damage dependence of blood perfusion rate and optical properties. Using this nonlinear model, it wasfound that the hyperemic ringformed at the periphery of the coagulationfront reduces heatpenetration significantly and the increased scattering near the tissue surface reduces the light energy deposition in the deep region. Thefinal damage depth would be overestimated by about 50% ifthe effect oftemperature and damage dependence of blood perfusion and opticalproperties modeling is disregarded.

AB - The dynamic evolution of the coagulation front in laser irradiated prostate tissue is simulated using a nonlinear finite element method (NFEM) which takes into account the temperature and thermal damage dependence of blood perfusion rate and optical properties. Using this nonlinear model, it wasfound that the hyperemic ringformed at the periphery of the coagulationfront reduces heatpenetration significantly and the increased scattering near the tissue surface reduces the light energy deposition in the deep region. Thefinal damage depth would be overestimated by about 50% ifthe effect oftemperature and damage dependence of blood perfusion and opticalproperties modeling is disregarded.

UR - http://www.scopus.com/inward/record.url?scp=0000330097&partnerID=8YFLogxK

U2 - 10.1117/12.209911

DO - 10.1117/12.209911

M3 - Conference article

AN - SCOPUS:0000330097

SN - 0277-786X

VL - 2391

SP - 443

EP - 450

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Laser-Tissue Interaction VI 1995

Y2 - 1 February 1995 through 8 February 1995

ER -

The role of dynamic changes in blood perfusion and optical properties in thermal coagulation of the prostate

Abstract

Bibliographical note

ASJC Scopus subject areas

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