Abstract
We prepared amino acid-derived diacetylene monomers using solid-phase organic synthesis. The solid-phase synthetic method allowed for the rapid and efficient preparation of functional diacetylenes. Amino acids having hydrophobic sidechains such as alanine, leucine, and phenylalanine, as well as hydrophilic sidechains such as aspartic acid and lysine, were successfully coupled to the diacetylene lipid. The diacetylene monomers prepared in this way were subjected to routine procedures for the generation of polydiacetylene vesicles. Depending on the nature of the side-chains, pink to blue colored polydiacetylenes were generated.
Original language | English |
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Pages (from-to) | 253-256 |
Number of pages | 4 |
Journal | Macromolecular Research |
Volume | 13 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2005 Jun |
Keywords
- Amino acids
- Diacetylene
- Solid-phase synthesis
ASJC Scopus subject areas
- Chemical Engineering(all)
- Organic Chemistry
- Polymers and Plastics
- Materials Chemistry