The Structure–property Relationships of Clinically Approved Protein Kinase Inhibitors

Keyphrases

• Structure-property Relationships 100%
• Protein Kinase Inhibitors 100%
• Physicochemical Properties 50%
• Structure-activity Relationship 50%
• Pharmacokinetic Properties 50%
• Lead Optimization 50%
• Drug Design 50%
• Medicinal Chemistry 50%
• Biological Properties 25%
• Property Data 25%
• Drug Discovery 25%
• Drug-like 25%
• Optimization Study 25%
• Design Effort 25%
• Small Molecule Drugs 25%
• Drug Attrition 25%
• Attrition Rate 25%
• General Guidelines 25%
• Property-based Drug Design 25%
• Modern Drug Discovery 25%
• Complex Drug 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Protein Kinase Inhibitor 100%
• Drug Development 75%
• Drug Discovery 50%
• Pharmaceutical Chemistry 50%
• Pharmacokinetics 50%
• Structure Activity Relationship 25%