Abstract
Dual-modal in vivo tumor imaging and photodynamic therapy using hexagonal NaYF4:Yb,Er/NaGdF4 core-shell upconverting nanoparticles combined with a photosensitizer, chlorin e6, is reported. Tumors can be clearly observed not only in the upconversion luminescence image but also in the magnetic resonance image. In vivo photodynamic therapy by systemic administration is demonstrated under 980 nm irradiation.
Original language | English |
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Pages (from-to) | 5755-5761 |
Number of pages | 7 |
Journal | Advanced Materials |
Volume | 24 |
Issue number | 42 |
DOIs | |
Publication status | Published - 2012 Nov 8 |
Keywords
- luminescence
- magnetic resonance imaging
- nanoparticles
- photodynamic therapy
- upconversion
ASJC Scopus subject areas
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering