Thinking Inside the Box: Endogenous α-Anomeric Lipid Antigens

  • Jessica Kim
  • , Ji Hyung Kim
  • , Florian Winau*
  • *Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

Abstract

The most powerful iNKT cell antigen is α-galactosylceramide (α-GalCer), derived from the marine sponge. However, α-anomeric glycolipids are thought to be absent in mammals. In this issue of Immunity, Kain etal., (2014) demonstrate the presence of mammalian α-linked glycosylceramides, such as α-GalCer. The most powerful iNKT cell antigen is α-galactosylceramide (α-GalCer), derived from the marine sponge. However, α-anomeric glycolipids are thought to be absent in mammals. In this issue of Immunity, Kain etal. demonstrate the presence of mammalian α-linked glycosylceramides, such as α-GalCer.

Original languageEnglish
Pages (from-to)505-506
Number of pages2
JournalImmunity
Volume41
Issue number4
DOIs
Publication statusPublished - 2014 Oct 16
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2014 Elsevier Inc.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being
  2. SDG 14 - Life Below Water
    SDG 14 Life Below Water

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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