@inproceedings{f48540c4f8924c31bb6910149b3d7823,
title = "Three-dimensionally patterned cardiomyocytes with high activity for powering bio-hybrid microdevices",
abstract = "We have demonstrated a simple method for patterning cardiac muscle cells with high activity on a micron scale for powering bio-hybrid microdevices. The morphology and mobility of patterned cardiac muscle cells within micro wells were analyzed with different topographical heights of the barrier. We found that three-dimensionally grown cardiac cells mediated by a higher physical harrier generated higher contraction force with fasler beating frequency than those of cells attached to the collagen-coated surface on the culture dish (control), suggesting that control over cell growth and shape would be critical for potential engineered cellular motors. Thus, the micropatterned cardiac muscle cells presented here would provide a primary platform for building up 3-D bioactuated microdevices including an engineered cell motor.",
keywords = "Bio-hybrid microdevice, Bioactuator, Capillary lithography, Cardiac muscles, Cell patterning",
author = "Kim, {Deok Ho} and Jungryul Park and Suh, {Kahp Y.} and Pilnam Kim and Choi, {Seung Kyu} and Lee, {Sang Ho} and Byungkyu Kim",
year = "2005",
doi = "10.1109/MMB.2005.1548436",
language = "English",
isbn = "0780387112",
series = "2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology",
pages = "233--236",
booktitle = "2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology",
note = "2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology ; Conference date: 12-05-2005 Through 15-05-2005",
}