Thrombosis in Behçet's disease: A Behçet's disease patient with complete thrombotic obstruction of IVC and both iliac veins and decreased protein S activity

Behçet's disease represents a multisystemic inflammatory disease characterized by recurrent oral ulcers, genital ulcers, and uveitis. Although vascular attack and thrombosis are not major complications in Behçet's disease, they can still pose risks that must not be overlooked. In this paper, we reported that a 25-year-old female Behçet's disease patient with complete thrombotic obstruction of the inferior vena cava that was successfully treated by aspiration thrombectomy and balloon angioplasty. The procedure produced marked symptomatic improvement. Currently, data about the treatment and the prophylaxis of thrombotic events in Behçet's disease are lacking. In this case report, we hope to discuss the future direction of such studies, how we understand the mechanism of Behçet's disease hypercoagulability, and which treatments can improve thrombotic tendencies in Behçet's disease.