Topological Adaptation of Transmembrane Domains to the Force-Modulated Lipid Bilayer Is a Basis of Sensing Mechanical Force

Keyphrases

• Adaptation 100%
• Mechanical Force 100%
• Transmembrane Domain 100%
• Lipid Bilayer 100%
• Mechanical Stimulation 50%
• Integrin 50%
• Mechanosensor 50%
• Adhesion Receptors 33%
• Sense-and-respond 33%
• Integrin Activation 33%
• Bilayer Model 33%
• Osmotic Pressure 16%
• Liposomes 16%
• Shear Stress 16%
• Ion Channels 16%
• Lipids 16%
• Interactome 16%
• Topological Transformation 16%
• Surrounding Environment 16%
• Prototypic 16%
• Bona Fide 16%
• Cell-free 16%
• Physical State 16%
• Signaling Events 16%
• Domain-domain Interaction 16%
• Mechanosensitivity 16%
• Lipid Environment 16%
• Membrane Curvature 16%
• Lipid Nanodiscs 16%
• Physical Deformation 16%
• Intracellular Activation 16%

Biochemistry, Genetics and Molecular Biology

• Lipid Bilayer 100%
• Transmembrane Domain 100%
• Integrin 83%
• Lipid 50%
• Conformation 16%
• Shear Stress 16%
• Interactome 16%
• Mechanosensitivity 16%
• Membrane Curvature 16%
• Ion Channel 16%