Toward Biomimetic Scaffolds for Tissue Engineering: 3D Printing Techniques in Regenerative Medicine

Justin J. Chung, Heejung Im, Soo Hyun Kim, Jong Woong Park, Youngmee Jung

Research output: Contribution to journalReview articlepeer-review

77 Citations (Scopus)


Three-dimensional (3D) printing technology allows fabricating complex and precise structures by stacking materials layer by layer. The fabrication method has a strong potential in the regenerative medicine field to produce customizable and defect-fillable scaffolds for tissue regeneration. Plus, biocompatible materials, bioactive molecules, and cells can be printed together or separately to enhance scaffolds, which can save patients who suffer from shortage of transplantable organs. There are various 3D printing techniques that depend on the types of materials, or inks, used. Here, different types of organs (bone, cartilage, heart valve, liver, and skin) that are aided by 3D printed scaffolds and printing methods that are applied in the biomedical fields are reviewed.

Original languageEnglish
Article number586406
JournalFrontiers in Bioengineering and Biotechnology
Publication statusPublished - 2020 Nov 4

Bibliographical note

Funding Information:
This research was supported by the KIST Institutional Program (2V08550). This work was partially supported by the Nano-Material Technology Development Program (NRF-2018M3A7B4071106) through the National Research Foundation of Korea and a National Research Foundation of Korea grant (NRF-2020R1C1C1012881) funded by the Ministry of Science and ICT (MSIT).

Publisher Copyright:
© Copyright © 2020 Chung, Im, Kim, Park and Jung.


  • 3D printing
  • bioink
  • regenerative medicine
  • scaffold
  • tissue engineering

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Histology
  • Biomedical Engineering


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